José N. Reyes, Jr., P.E., Nuclear Engineering Ph.D. and M.S. Univ. of Maryland, B.S. Univ. of Florida is the Co-founder and Chief Technology Officer of NuScale Power. He is co-inventor of the NuScale small modular reactor with over 110 patents granted or pending in 20 countries. He is an expert on nuclear plant scaling, passive safety, and testing. He is Professor Emeritus and former head of the Dept. of Nuclear Engineering at Oregon State University. He is an ANS Fellow and Member of the National Academy of Engineering.
Mekhail Anwar, MD PhD
Associate Professor, Radiation Oncology
profiles.ucsf.edu/mekhail.anwar | anwarlab.ucsf.edu
We will discuss how to personalize cancer therapy through the development of new integrated circuit-based platforms for detecting both the delivery of charged particle therapy (CPT).
Real-time in vivo dosimetry - at the single particle level - holds the key to unlocking the power of personalized theranostics with both 𝛼 and β particles and the precision of proton therapy. The impact of theranostics using Lu177 - a β emitter - is already being felt across neuroendocrine and prostate cancers. Notably, 𝛼 particles deposit over 100X more energy over just 50 µm - making them a much more powerful - and potentially preciscse - therapeutic. However, this enthusiasm is tempered by the highly variable biodistribution making in vivo dosimetry essential to safe, personalized delivery. Similarly, range uncertainty is a major limiting factor in precision targeting of charged particle therapy, and would benefit from real-time in vivo dosimetry. To address these dual challenges, we have developed SENTRI - a mm2 chip capable of single CPT measurements from within tissue - and will discuss how efforts to fuse proton therapy and personalized theranostics can improve outcomes in patients with aggressive cancers.
Mekhail Anwar is a Physician-Scientist and Associate Professor in the Department of Radiation Oncology at the University of California, San Francisco (UCSF), focusing on developing microfabricated sensors and computer chip technology (‘integrated circuits’ or ICs) for cancer detection within the body. Educated at UC Berkeley in Physics, he completed his MD at UC San Francisco, and went to the Massachusetts Institute of Technology where his Ph.D. in electrical engineering focused on using ICs for biosensing. He returned to complete his residency in Radiation Oncology at UCSF and continued as faculty, where he earned the DOD Prostate Cancer Research Program Physician Award for his work in cancer imaging. He is the recipient of the NIH Trailblazer Award for developing chip-scale imagers for cancer and was recently awarded the NIH (DP2) New Innovator Award for in vivo imaging of immunotherapy response.
The global nuclear industry has for decades used sites like Stonehenge as models for designs for long-term markers to be placed over nuclear waste repositories to ensure they are not violated in distant, imagined futures. In the US, the resulting proposal would produce a pre-formed archaeological site, a ruin that would qualify for listing as a World Heritage site in the future. This talk questions the way planners thought about materials and human intentions from the perspective of an archaeological sensibility on how materials endure and decay and what people in the past expected would happen when they created the structures we recognize as monuments today.
Rosemary Joyce received the PhD from the University of Illinois-Urbana in 1985, based archaeological fieldwork in Caribbean Honduras. A curator and faculty member in anthropology at Harvard University from 1985 to 1994, she moved to the University of California, Berkeley in 1994, initiating new archaeological fieldwork in Honduras on the emergence of settled farming villages before 1500 BC. This began her explorations of the liveliness of geological materials, and the intentions of people in the past when they built features today seen as monuments. She is the author of ten books, the latest The Future of Nuclear Waste: What Art and Archaeology Can Tell Us About Securing the World’s Most Hazardous Material (2020, Oxford University Press).
Dr. Craig Levin is a Professor in the Department of Radiology with courtesy appointments in the Departments of Physics, Electrical Engineering, and Bioengineering at Stanford University. He is a founding Member of the Molecular Imaging Program at Stanford (MIPS), and faculty member of the Stanford’s Bio-X Program, Cancer Institute, Cardiovascular Institute, and Neurosciences Institute. He is director and PI of the NIH-NCI funded Stanford Molecular Imaging Scholars (SMIS) post-doctoral training program, and Co-Director of the Stanford Center for Innovation in In Vivo Imaging (SCI^3). Dr. Levin’s also directs a 25-member research laboratory whose research interests are to explore new concepts in imaging instrumentation and computational algorithms for advancing our ability to visualize and quantify molecular and cellular pathways of disease in living subjects. To support this work he has received numerous grants from NIH, DOE, DOD, NSF, industrial sponsorship from companies such as GE, Siemens, and Philips, as well as research awards from numerous non-profit foundations. Dr. Levin has over 170 peer-reviewed publications and 26 awarded patents.
Molten fluoride salts are ionic liquids that are employed in nuclear reactors as coolant or nuclear fuel solvents. 2LiF-BeF2 (FLiBe) is an ionic liquid that is of particular interest for application in nuclear reactors due to its neutronic properties. While the fluoride salts are ionic liquids, the beryllium constituent is known to form partly covalent associates with the fluorine, leading for formation of complex ions in the ionic melt. The implications of this complexation on the chemical and thermophysical properties of the salt are only partly understood. This talk will provide examples of unexpected observations in molten fluoride salts relevant to nuclear applications, including reactions of FLiBe with hydrogen.
Raluca Scarlat is an assistant professor at UC Berkeley, in the Department of Nuclear Engineering. Professor Scarlat has a Ph.D. in Nuclear Engineering from UC Berkeley and a B.S. in Chemical and Biomolecular Engineering from Cornell University. Raluca Scarlat’s research focuses on chemistry, electrochemistry and physical chemistry of high-temperature inorganic fluids and their application to energy systems. She has experience in design and safety analysis of fluoride-salt-cooled high-temperature reactors (FHRs) and Molten Salt Reactors (MSRs), and high-temperature gas cooled reactors (HTGRs). Her research includes safety analysis and design of nuclear reactors and engineering ethics.
Many University TRTRs were shut down in the 1980s & 1990s as student enrollments waned. In the 2000s, student enrollment in nuclear engineering and enthusiasm for carbon-free nuclear energy has rebounded mightily, but no new university TRTRs have been built in nearly 30 years. Simultaneous with this widening gap in hands-on training, unprecedented federal funding to demonstrate and commercialize advanced reactors has been distributed to companies promising a bright future for advanced nuclear energy. But, in this future, who will objectively test these reactors, train their operators, educate their reactor engineers, and improve the technology through innovative experiments?In this talk, I'll suggest that universities remain poised to play many of these roles in the future of next-generation nuclear reactor deployment and university campuses are uniquely suited for early deployments. We at UIUC envision a next-generation university test, research, and training reactor that could underpin advanced reactor commercialization toward national leadership in a clean, sustainable energy future. Our vision for the deployment of a next-generation university TRTR aims to amplify the profound expertise at campuses in research, education, and power production to address the urgent need for advanced reactor prototype testing as well as next-generation research toward integration with carbon-free energy technologies. I will describe a vision of the future in which universities and their research can and must play a significant role in prototype testing next-generation reactors, support commercial licensing and deployment, conduct operations research, drive innovations in associated technologies, and train a next-generation workforce to operate and maintain these next-generation devices.
Dr. Kathryn D. Huff is an Assistant Professor in the Department of Nuclear, Plasma, and Radiological Engineering at the University of Illinois at Urbana-Champaign where she leads the Advanced Reactors and Fuel Cycles Research Group. She is additionally a Blue Waters Assistant Professor with the National Center for Supercomputing Applications. She was previously a Postdoctoral Fellow in both the Nuclear Science and Security Consortium and the Berkeley Institute for Data Science at the University of California - Berkeley. She received her PhD in Nuclear Engineering from the University of Wisconsin-